Exercises
Define Glomerular Filtration Rate (GFR)
Glomerular Filtration Rate (GFR) is the amount of glomerular filtrate formed in both kidneys per minute.
In a healthy adult, GFR is approximately 125 mL/minute, which amounts to about 180 litres of filtrate per day.
GFR is determined by the glomerular capillary blood pressure, which drives ultrafiltration of blood through the three-layered filtration barrier: the glomerular endothelium, the basement membrane, and the podocyte epithelium of Bowman's capsule.
Answer: GFR is the volume of glomerular filtrate formed per minute — approximately 125 mL/min (180 L/day) in a healthy adult.
